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Methanesulfonic Acid (MSA), also known as methanesulphonic acid or mesylic acid, is the simplest member of the alkylsulfonic acid family, recognized for its strong acidity and non-oxidizing nature. This organic acid acts as a critical link between organic and inorganic chemistry, featuring a single carbon atom in its methyl group, which classifies it as a C1 compound in organic chemistry. MSA is fully miscible with water and organic solvents such as alcohols and diethyl ether, making it exceptionally versatile. Industrially, MSA finds applications in catalysis (polymerization and other organic reactions), electroplating (achieving uniform metal deposits), fine chemical synthesis (API salt preparation), and cleaning (rust and scale removal). Its role as a reaction solvent in acidic, non-oxidizing environments and as a neutralizing agent for soluble salt formation further underscores its adaptability. The salts derived from MSA, known as methanesulfonates or mesylates, extend its functionality across diverse processes.
Chemical Name
Methanesulfonic Acid (MSA)
CAS #
75-75-2
EC #
200-898-6
Molecular Formula
CH4O3S
InChI Key
AFVFQIVMOAPDHO-UHFFFAOYSA-N
Synonyms
Methanesulfonic acid; Methylsulfonic acid; MCAT 1201; NSC 3718; Scaleva; Mesylic acid; Lutropure MAS; Lutropur MSA; Lutropur G 100; Circuposit Neutralizer; 3319/4190; Methanesulfonic acids; Mesylates; Lutropur MSA 100; Lutropur M
Product Group 1
Additives, AcidsProduct Group 2
Lubricants & Greases, Pharma, CASE, Plastic & Rubber, Oil & Gas167 °C @ Press: 10 Torr
1.4812 g/cm³ at 18 °C
20 °C
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The CAS registry number for Methanesulfonic Acid (MSA) is 75-75-2.
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