CAS: 25322-68-3

PEG 300 NF, or polyethylene glycol 300, is a hydrophilic polymer widely recognized for its high solubility in water and its gentle, non-irritating nature. Unlike other products in its category, PEG 300 NF is designed to meet stringent pharmaceutical standards, making it a trusted choice for various applications. Its importance in the pharmaceutical industry can be traced back to its ability to enhance drug solubility and bioavailability, while its history reflects a continuous evolution in chemical development for safe consumption. PEG 300 NF belongs to the categories of excipients and solvents, frequently used in formulations and various therapeutic products.

PEG 300 NF is not only used in pharmaceuticals and personal care, but its water-soluble properties also make it useful in the creation of eco-friendly cleaning products, offering an alternative to harsher chemicals.

Chemical Properties

  • CAS: 25322-68-3

  • Molecular Formula: H(OCH2CH2)nOH

  • Molecular Weight: Min. 285 , Max. 315

  • Hydroxyl Value mg KOH/g:  Min. 356 , Max. 394

  • Free Ethylene Oxide ppm: Max. 10

Physical Properties

  • Appearance: Clear, colorless to pale yellow viscous liquid

  • Odor: Odorless

  • Solubility: Completely soluble in water and alcohols

Applications in Pharma

PEG 300 NF serves as a vital component in the pharmaceutical sector, where it acts as a solvent, emulsifier, and humectant in various formulations. Its ability to enhance drug delivery systems makes it invaluable in improving the stability and effectiveness of medications. It is commonly used in ointments, creams, and oral solutions, ensuring a smooth application and consistent results.

Applications in Other Industries

PEG 300 NF finds significant applications beyond pharmaceuticals, including:

  • Agriculture: Used as a surfactant in pesticides to improve spreadability and adherence.

  • Personal Care: Incorporated into lotions and creams for its moisturizing properties.

  • CASE (Coatings, Adhesives, Sealants, Elastomers): Enhances the performance and stability of formulations.

  • HI&I (Household, Industry, and Institutions): Serves as a cleaning agent and surfactant in household products.

  • Plastics and Rubber: Acts as a processing aid to improve flow and reduce viscosity.

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